Sofovir (Sofosbuvir)



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Sofovir (Sofosbuvir) is a type of drug used to treat Hepatitus C and works on HCV genotypes 1, 2, 3 and 4. Sofosbuvir has to be used in combination with other HCV medications such as Pegylated interferon and Ribavirin.

Brand Name : Sofovir
Active Ingredients : Sofosbuvir
Manufacturer : Hetero
Country of Origin : India
Intended Patient : Unisex

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Sofovir (Sofosbuvir) is indicated in combination with under medicinal products for the treatment of chronic hepatitis C in genotype 1, 2, 3 and 4. It is suitable to treat patients awaiting liver transplantation and those with HCV/HIV-1 co-infection.

Sofosbuvir directly targets the Hepatitus C virus to stop it from making copies of itself in the liver and makes it harder for the virus to multiply.

Dosage and Administration

The recommended dose of Sofovir is one 400mg tablet, taken orally, once daily with or without food. Sofosbuvir should be used in combination with ribavirin or in combination with pegylated interferon and ribavirin for the treatment of chronic hepatitus C (CHC) in adults. 

The recommended dosing method in treatment for HCV patients as follows:

1. HCV genotype 1 or 4 takes Sofovir (Sofosbuvir) with Ribavirin and Pegylated interferon for 12 weeks.
2. HCV genotype 2 takes Sofovir (Sofosbuvir) with Ribavirin for 12 weeks (without interferon).
3. HCV genotype 3 takes Sofovir (sofosbuvir with Ribavirin for 24 weeks (without interferon).

(Interferon is injected under the skin, and ribavirin is taken by mouth.)

The above information is only a recommendation, for more details and professional advice, you should check with your doctor or health care provider.

Side effects

The common side effects of taking Sofovir (Sofosbuvir) as below:

  • Headache
  • Insomnia
  • Tiredness
  • Nausea
  • Dizziness

Some side effects can be serious. If you have unusual experiences or problems, you should contact your doctor or health care provider immediately.


Do not take this Sofovir (Sofosbuvir) alone.

Using this Sofovir (Sofosbuvir) together with ribavirin while you are pregnant can harm your unborn baby.  The combination of Sofovir (Sofosbuvir), Ribavirin and Pegylated interferon can cause serious birth defects. If a pregnancy occurs to mother, while either partners are using these medicines at the time, tell your doctor right away.

To make sure you are not pregnant, your doctor may ask you to have a pregnancy test before you start using this medicine. You must have a negative pregnancy test before you will be allowed to use this medicine with ribavirin.

If you are on any other drugs or supplements, breast-feeding, or decide to change dosage or stop taking Sofovir (Sofosbuvir), you should discussed with your doctor before hand.

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